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You are here: Home / Symptoms of CIRS / A Guide to Identifying CIRS Symptom Clusters
A Guide to Identifying CIRS Symptom Clusters

A Guide to Identifying CIRS Symptom Clusters

Last Updated on: February 21, 2025 by Mark Volmer

A Guide to Identifying CIRS Symptom Clusters

When Linda, a busy 52-year-old mother of two, began feeling exhausted all the time, she assumed it was just age catching up with her. But as time went on, her symptoms multiplied—she had trouble remembering words, her vision blurred, and she developed odd aches that never seemed to go away. Despite seeing several doctors, no one could provide a clear diagnosis. It wasn’t until she stumbled across information about Chronic Inflammatory Response Syndrome (CIRS) that things started making sense.

Could these seemingly unrelated symptoms all be connected?

What is CIRS?

CIRS is a chronic, multi-system illness triggered by biotoxin exposure, often from water-damaged buildings. Patients like Linda experience a wide range of symptoms across different bodily systems, making it hard to diagnose. The condition doesn’t present itself with just one or two symptoms, but rather with clusters of them—groups of symptoms that seem to attack different parts of the body simultaneously. By recognizing these symptom clusters, it becomes much easier to identify CIRS.

In fact, researchers have identified thirty-seven common symptoms of CIRS, which can be grouped into thirteen distinct clusters. Understanding these clusters is crucial because if you experience symptoms from at least eight of these thirteen clusters, you are highly likely to have CIRS.

The 13 Symptom Clusters of CIRS

Let’s break down these symptoms into their corresponding clusters, so you can better understand the condition and recognize if these symptoms are impacting your life.

Cluster #1:

•Fatigue
•Weakness

Fatigue is one of the most prominent symptoms of CIRS. It goes beyond normal tiredness; CIRS-related fatigue is debilitating and can persist even after a full night’s sleep. Weakness often accompanies this fatigue, making simple tasks like climbing stairs feel overwhelming.

A study published in the Journal of Occupational and Environmental Medicine found that over 80% of CIRS patients report persistent fatigue, making it the most common symptom of the illness .

Cluster #2:

•Headaches

Chronic headaches, often mistaken for tension or migraines, are another common symptom of CIRS. The exact cause of these headaches varies, but it is often linked to inflammation triggered by biotoxin exposure.

Headaches alone may not seem unusual, but when combined with other symptoms, they can indicate a deeper issue.

Cluster #3:

•Aches
•Cramps

CIRS can cause widespread body aches that are often dismissed as fibromyalgia or arthritis. Muscle cramps and stiffness can also occur, making movement difficult.

Cluster #4:

• Pain – sharp pain, clawing pain, electrical pain, or ice pick pains

One of the lesser-discussed symptoms of CIRS is the experience of sharp, stabbing pains, often described as “ice pick” pains. These can occur anywhere in the body and are often sudden and severe, resembling nerve pain.

These unusual pains are often missed by healthcare providers who aren’t familiar with CIRS, which delays diagnosis for many patients.

Cluster #5:

•Light sensitivity
•Red eyes
•Blurred vision
•Tearing

If you’ve ever been told that you have “red eyes” or noticed your eyes are unusually sensitive to light, this could be another sign of CIRS. Blurred vision, frequent tearing, and difficulty adjusting to bright environments are common issues for those suffering from CIRS.

Cluster #6:

•Shortness of breath
•Cough
•Sinus issues

Breathing difficulties can develop in those with CIRS, as the body’s response to toxins may inflame the respiratory system. Coughing and sinus congestion are common symptoms, but they are often attributed to other causes like allergies or asthma.

Cluster #7:

•Abdominal pain
•Diarrhea
•Acid reflux

Digestive problems, particularly unexplained abdominal pain and diarrhea, are frequent in CIRS patients. Many experience symptoms similar to irritable bowel syndrome (IBS), while others struggle with acid reflux that doesn’t seem to have a clear cause.

Cluster #8:

•Joint pain
•Morning stiffness

Like many inflammatory conditions, CIRS can cause significant joint pain and morning stiffness. This stiffness usually subsides throughout the day, but it can make getting out of bed a challenge.

Cluster #9:

•Memory challenges
•Word recollection issues
•Confusion
•Disorientation

Cognitive difficulties are a hallmark of CIRS. Many patients, like Linda, struggle with memory problems, confusion, and an inability to concentrate. Even simple tasks can become overwhelming, and some describe their experience as “brain fog.”

In severe cases, these cognitive symptoms can mimic the early stages of dementia, making diagnosis even more complicated  .

Cluster #10:

•Mood swings
•Appetite swings
•Sweats
•Temperature regulation issues

Mood changes are another common but overlooked symptom of CIRS. Rapid shifts in mood, paired with fluctuations in appetite, make it hard for patients to feel stable. Sweating and issues with body temperature regulation—such as feeling too hot or too cold—are also common.

Cluster #11:

•Excessive thirst
•Frequent urination
•Static shocks

Unquenchable thirst and frequent urination can be frustrating for CIRS patients. Some even experience static shocks more often than usual, although the reasons for this are not yet fully understood.

Cluster #12:

•Numbness
•Tingling
•Metallic taste

CIRS patients may experience numbness or tingling in their extremities, alongside abnormal tastes, particularly a metallic taste in their mouths. These symptoms are often subtle but can add to the general discomfort.

Cluster #13:

•Vertigo
•Tremors
•Skin sensitivity

CIRS can affect the nervous system, leading to vertigo, tremors, and heightened skin sensitivity. These symptoms are sometimes misdiagnosed as neurological disorders when, in fact, they are related to biotoxin exposure.

Identifying CIRS symptom clusters – the right way

If this is your first introduction to CIRS and the associated symptom clusters, you probably went through each of the 37 symptoms and mentally checked off every symptom that sounds familiar.

That’s a fantastic first step. But proper symptom analysis should be done by a qualified CIRS practitioner.

Why?

The trained practitioner has a duty to further define each of the symptoms you say yes to. For example, if you say yes to having fatigue, the practitioner should define the following:

  • When is the fatigue present (time of day)?
  • What kind of day-to-day activity can you tolerate without experiencing fatigue?
  •  If you had a good day and tried to do more than normal, what would happen the following day?

These clarifying questions are essential to properly define the symptom. This needs to be done for each of the thirty-seven symptoms.

For a lot of CIRS patients, some symptoms have been present for so long that they are considered ‘normal’. Only through proper examination of each symptom can a practitioner determine if ‘normal’ for a possible CIRS patient is the same as ‘normal’ for someone not suffering from CIRS.

Connecting the Dots: Could it be CIRS?

If you’re dealing with symptoms from at least eight of these clusters, there’s a strong possibility that CIRS is the underlying cause. According to the research led by Dr. Ritchie Shoemaker, CIRS is often undiagnosed or misdiagnosed due to the wide range of symptoms and their overlap with other conditions . The key is identifying the clusters. For someone like Linda, recognizing the patterns across her body was the turning point in her journey toward healing.

How to Get Help

At Flourish Clinic, we specialize in helping CIRS patients identify these symptom clusters and provide customized treatment plans that address their unique needs. With expert knowledge in biotoxin-related illnesses, our clinic can guide you through testing and treatment protocols to help you reclaim your health. If you believe you may have CIRS, our team can help you find the right path forward.

CIRS is a complex, multi-system illness, but identifying its symptom clusters is the first step toward understanding it. If you’re experiencing persistent and seemingly unrelated symptoms from multiple clusters, it may be worth investigating whether CIRS is the cause. The sooner you identify the connection, the sooner you can start healing.

Schedule a complimentary call today to find out if your symptoms may be caused by CIRS.

Could your collection of symptoms be a sign of CIRS?

 

Mark Volmer has attained the highest level of Shoemaker Protocol certification, and is one of only two of Canada’s Shoemaker Protocol practitioners. The Shoemaker Protocol is the only scientifically proven method of treating CIRS.

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